Key Takeaways
A national study found that 82 in every 100 people in India with current wheeze symptoms had never been clinically diagnosed with asthma. Spirometry, the breathing test that confirms airflow obstruction, is not part of routine practice across much of Indian primary care. Without it, doctors treat symptoms rather than confirmed diagnoses. Several conditions produce identical symptoms to asthma, each requiring a different treatment. If you have been managing breathlessness or a persistent cough without a confirmed breathing test, this matters.
A familiar scene at the clinic
Meena is 47 years old. She lives in a second-floor flat in Pune. Every time she climbs those stairs, she stops at the top, hand on the railing, waiting for her breath to come back. It has been like this for two years.
Her family doctor prescribed a reliever inhaler after her first visit. It helped a little. Then he added a tablet for acid reflux when she mentioned a nagging cough. That helped a little too. But neither made the breathlessness go away entirely. Her file now has three different diagnoses scrawled on different pages: "asthma," "possible COPD," and "GERD."
Meena has never had a breathing test. Not because her doctor didn't want to order one. There is no machine for it at her clinic. Her story is not unusual, it is the norm across India, and the consequences of that gap are serious and largely preventable.
What the evidence says
Breathlessness, persistent cough, and wheezing are among the most common reasons adults in India visit a primary care doctor. Yet a large body of peer-reviewed research now shows that the single most reliable way to confirm or rule out the cause of those symptoms is almost never used.
That test is called spirometry, a breathing test that measures how much air your lungs can push out and how fast. It takes about 15 minutes. It is painless. And it is the international gold standard for confirming conditions that block airflow in the lungs, such as asthma and COPD (chronic obstructive pulmonary disease).
About 82 in every 100 people in India with current wheeze symptoms had never been clinically diagnosed with asthma. Among those reporting symptoms of severe asthma, about 70 in every 100 were also undiagnosed. Source: Singh S, Salvi S, et al. Global Asthma Network study, ERJ Open Research, 2022.
Get StartedCost and access are the other barriers. Where a spirometer is not available nearby, or where the test is not affordable, doctors are left working from reported symptoms rather than a confirmed measurement of airflow.
What happens in the absence of the test
Doctors make a reasonable but limited judgment call: they prescribe treatment based on symptoms alone, without a confirmed diagnosis. This approach is sometimes appropriate, but carries real risks when used long-term. Many conditions cause breathlessness and cough, asthma is one, but it is far from the only one:
- check_circleCOPD (chronic obstructive pulmonary disease), progressive airflow limitation, distinct from asthma in cause and management.
- check_circleBronchiectasis, permanent widening and scarring of the airways, requiring different treatment and monitoring.
- check_circleVocal cord dysfunction, the vocal cords moving incorrectly, mimicking asthma but not responding to inhalers.
- check_circleEosinophilic bronchitis, a specific type of airway inflammation that responds to different treatment than standard asthma.
- check_circleGERD-related cough, stomach acid irritating the airway, often confused with asthma at night.
- check_circleACE inhibitor cough, a side effect of certain blood pressure medications, which stops when the medication is changed.
Each condition has a different cause and requires a different treatment. Without spirometry, and in some cases further specialist tests, it is not possible to confidently tell them apart. This is also relevant to conditions beyond the lungs. Neuromuscular weakness affecting the breathing muscles can produce breathlessness that closely mimics airway disease but requires a completely different evaluation pathway, sometimes including a neurology specialist assessment.
What this means for your case
If you or someone in your family has been managing breathlessness, a persistent cough, or recurrent chest tightness, and has never had a confirmed breathing test, these are specific questions worth raising with your doctor:
- check_circle"Has my diagnosis been confirmed with spirometry, or is it based on my symptoms alone?"
- check_circle"Could my symptoms have more than one cause at the same time?"
- check_circle"Is there a referral I can get to a centre where spirometry is available?"
- check_circle"If I have had a spirometry test already, what did the results show, and was a reversibility test done as well?" (A reversibility test checks whether the blockage improves after using a reliever inhaler. This helps distinguish asthma from COPD and other conditions.)
- check_circle"Are there other diagnoses that should be ruled out before I continue on my current treatment?"
These are standard clinical questions that a specialist would ask as a matter of course. In a 10-minute primary care consultation, they often go unasked. Understanding what a pulmonology second opinion involves can help you prepare for that conversation.
What a subspecialist review evaluates
When a patient's breathing symptoms have not been fully resolved by primary care management, a review by a board-certified pulmonologist adds a different kind of depth. The specialist does not simply review whether the current medication seems reasonable, they ask whether the diagnosis itself is correct. A specialist review typically evaluates:
- check_circleWhether the existing evidence, test results, clinical notes, medication response, is sufficient to confirm the stated diagnosis, or whether it points to an alternative.
- check_circleWhich conditions in the differential have been ruled out, and how, COPD, bronchiectasis, vocal cord dysfunction, eosinophilic bronchitis, GERD-related cough, and ACE inhibitor cough all require specific testing to exclude.
- check_circleWhether spirometry results, if available, were interpreted correctly, including the reversibility test and the specific pattern of airflow limitation.
- check_circleWhether the current treatment is matched to the confirmed diagnosis, or to a presumed one.
- check_circleWhat further investigations, if any, would change the management plan.
This kind of review does not replace your doctor or your ongoing care in India. It is an educational second opinion, a structured written review by a U.S. board-certified specialist that your own doctor can use to inform decisions. It provides clarity where the system has not yet had the resources to offer it.
Clarity is the starting point
India has some of the most skilled physicians in the world. The problem is not the quality of medical knowledge available. The problem is access, to the right test, at the right time, reviewed by the right person.
An unconfirmed diagnosis is not a failure. It is often the result of a system under pressure doing the best it can with what it has. But living on treatment that may or may not match your actual condition, for months or years, carries real costs: in quality of life, in medication side effects, and in delayed treatment for what may actually be wrong.
Tidbit Health connects patients in India with U.S. board-certified pulmonologists and other specialists for a written educational review of their case, delivered within 14 days. No travel. No appointment waitlists. A clear, written document you and your doctor can work from. If you have been managing breathlessness or a persistent cough without a confirmed diagnosis, a specialist review is a practical next step.
This article is for educational purposes only. It does not constitute a medical diagnosis, treatment recommendation, or prescription. These reviews do not replace your in-person physician relationship. No guarantee of specific outcomes is made. If you are in distress or experiencing a medical emergency, call your local emergency number immediately.
Sources & References
Frequently Asked Questions
What is spirometry and how is it different from a pulse oximeter?
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A pulse oximeter measures how much oxygen is in your blood at a single moment, it is useful but cannot confirm or rule out asthma or COPD. Spirometry is a breathing test that measures how much air your lungs can push out and how fast. It takes about 15 minutes and is the international gold standard for confirming conditions that block airflow in the lungs. A pulse oximeter can appear normal even in someone with significant airflow obstruction.
What conditions can mimic asthma symptoms?
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Several conditions produce breathlessness, cough, and chest tightness that can look identical to asthma on clinical examination: COPD (chronic obstructive pulmonary disease), bronchiectasis (permanent widening of the airways), vocal cord dysfunction, eosinophilic bronchitis, GERD-related cough (acid reflux irritating the airway), and ACE inhibitor cough (a side effect of certain blood pressure medications). Each requires a different treatment approach. Without spirometry and sometimes additional specialist tests, it is not possible to confidently tell them apart.
What is the reversibility test in spirometry?
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A reversibility test is done as part of spirometry. After measuring baseline lung function, the patient uses a reliever inhaler (such as salbutamol) and the test is repeated about 15 minutes later. If the airflow obstruction improves significantly after the inhaler, this points toward asthma rather than COPD, because asthma involves reversible airway narrowing, whereas COPD typically does not. This distinction changes the treatment plan significantly.
Why might I have asthma symptoms but test normal on a standard examination?
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Asthma symptoms can be intermittent, airflow may be completely normal between episodes. A standard clinical examination (listening to the chest with a stethoscope) may find nothing even in someone with significant asthma. Spirometry done during or shortly after a symptomatic period, or with a bronchoprovocation challenge, is more likely to capture the obstruction.
Can breathing problems be caused by something other than the lungs?
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Yes. Neuromuscular conditions affecting the breathing muscles can cause breathlessness that mimics lung disease, and these require a completely different evaluation pathway, sometimes involving a neurology specialist. Cardiac conditions, anaemia, and anxiety can also cause breathlessness. A thorough evaluation considers these possibilities alongside a lung-focused workup.
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